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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
35.76
Human Site:
S469
Identified Species:
65.56
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
S469
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
S616
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
S469
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Dog
Lupus familis
XP_534118
897
103170
S438
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
S463
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Rat
Rattus norvegicus
P33568
920
105007
S462
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
S460
K
S
E
E
E
R
L
S
I
Q
N
F
S
K
L
Chicken
Gallus gallus
Q90600
921
104417
S459
K
S
E
E
E
R
L
S
V
H
N
F
S
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
E451
E
S
M
L
K
S
E
E
K
R
L
S
V
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
P478
N
D
E
K
R
K
K
P
N
Y
D
V
T
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
T322
V
P
P
S
P
D
S
T
V
K
S
P
V
F
L
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
H537
T
A
E
A
Q
I
L
H
A
T
N
L
T
S
L
Maize
Zea mays
Q3LXA7
1010
111475
S521
R
A
E
S
Q
I
L
S
G
N
N
L
T
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
N.A.
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
33.3
N.A.
N.A.
40
N.A.
33.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
60
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
85
62
62
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
62
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
54
0
0
0
0
0
0
% I
% Lys:
62
0
0
8
8
8
8
0
8
8
0
0
0
62
0
% K
% Leu:
0
0
0
8
0
0
77
0
0
0
8
16
0
0
93
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
8
77
0
0
8
8
% N
% Pro:
0
8
8
0
8
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
54
0
0
0
8
0
% Q
% Arg:
8
0
0
0
8
62
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
70
0
16
0
8
8
70
0
0
8
8
62
16
0
% S
% Thr:
8
0
0
0
0
0
0
8
0
8
0
0
24
0
0
% T
% Val:
8
0
0
0
0
0
0
0
16
0
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _